Vivelle-Dot Transdermal Patch for Menopausal Symptom Relief

Image credit: drugs.com

What is Vivelle Dot & how does it work?

Vivelle-Dot is a patch that contains the estrogen hormone, estradiol. When applied to the skin as directed below, Vivelle-Dot releases estrogen through the skin into the bloodstream. What is Vivelle -Dot used for?

Can Vivelle Dot be used on breasts?

The adhesive side of Vivelle-Dot® (estradiol transdermal system) should be placed on a clean, dry area of the abdomen. Vivelle-Dot should not be applied to the breasts. Vivelle-Dot should be ... The adhesive side of Vivelle-Dot ® (estradiol transdermal system) should be placed on a clean, dry area of the abdomen.

What is Vivelle-Dot used for?

Vivelle-Dotes are used to treat certain symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Vivelle-Dot is also used to prevent postmenopausal osteoporosis, or to treat ovarian disorders. Vivelle-Dot may also be used for purposes not listed in this medication guide.

What happens if you overdose on Vivelle Dot?

Overdosage of estrogen may cause nausea and vomiting, and withdrawal bleeding may occur in females. The adhesive side of Vivelle-Dot® (estradiol transdermal system) should be placed on a clean, dry area of the abdomen. Vivelle-Dot should not be applied to the breasts. Vivelle-Dot should be ...

How does Vivelle-Dot work?

The system is designed to release estradiol continuously upon application to intact skin. Five dosage strengths of Vivelle-Dot are available to provide nominal in vivo delivery rates of 0.025, 0.0375, 0.05, 0.075, or 0.1 mg of estradiol per day via the skin.

When should Vivelle-Dot be used?

Patients should be started at the lowest dose. For treatment of moderate-to-severe vasomotor symptoms and vulvar and vaginal atrophy associated with the menopause, start therapy with Vivelle-Dot 0.0375 mg/day applied to the skin twice weekly.

What is Vivelle-Dot (estradiol transdermal system)?

Vivelle-Dot (estradiol transdermal system) contains estradiol in a multipolymeric adhesive. The system is designed to release estradiol continuously upon application to intact skin. Five dosage strengths of Vivelle-Dot are available to provide nominal in vivo delivery rates of 0.025, 0.0375, 0.05, 0.075, or 0.1 mg of estradiol per day via the skin.

Is Vivelle-Dot bioequivalent to Vivelle?

In a pharmacokinetic study, Vivelle-Dot was shown to be bioequivalent to Vivelle. In two controlled clinical trials with Vivelle, of 356 subjects, the 0.075 and 0.1 mg doses were superior to placebo in relieving vasomotor symptoms at Week 4, and maintained efficacy through Weeks 8 and 12 of treatment.

What Is Vivelle-Dot

1. https://www.drugs.com/mtm/vivelle-dot-skin-patch.html
2. https://www.medicine.com/drug/vivelle-dot
3. https://www.mayoclinic.org/drugs-supplements/estradiol-transdermal-route/proper-use/drg-20075306
4. https://www.rxlist.com/vivelle-dot-drug.htm
5. https://www.everydayhealth.com/drugs/vivelle-dot
6. https://www.webmd.com/drugs/2/drug-17081/vivelle-dot-transdermal/details
7. https://www.singlecare.com/prescription/vivelle-dot/what-is
8. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=03ab0226-b494-4607-8e8b-7381082fa780
9. https://www.pandiahealth.com/menopause/mht/patch/vivelle-dot-patch/

Vivelle-Dot Information

1. https://www.novartis.com/us-en/sites/novartis_us/files/Vivelle_DOT.pdf
2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20538slr019_vivelle_lbl.pdf
3. https://www.epocrates.com/online/drugs/3633/vivelle-dot
4. https://www.empr.com/drug/vivelle-dot/