Transmucosal Patches: Uses and Administration

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What is the difference between TDDs and transmucosal patches?

* In comparison to TDDS, mucosal surfaces do not have a stratum corneum. Thus, the major barrier layer to transdermal drug delivery is not a factor in transmucosal routes of administration. Hence transmucosal systems exhibit a faster initiation and decline of delivery than do transdermal patches.

What is a transdermal patch?

Patches are a unique technique offering the ability for transdermal drug delivery systems on demand. The limiting factors for transdermal delivery systems are the physicochemical and pharmacokinetic properties of an active drug enabling delivery across the skin.

What is transmucosal drug delivery?

Transmucosal drug delivery Transmucosal drug administration is an attractive alternative to oral and parenteral routes of administration, due to its non-invasive nature, and offering the possibility of self-administration, or administration by lay caregivers.

What is a buccal mucoadhesive patch?

Buccal mucoadhesive patch Buccal patches are the most common types of oral drug delivery systems which are usually prepared by casting a solution including a polymer, drug, and any excipients onto a surface.

What Is Transmucosal Patches

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603972/
2. https://www.sciencedirect.com/science/article/pii/S0168365911000332
3. https://decisionsindentistry.com/article/transmucosal-drug-delivery-in-the-oral-cavity/
4. https://www.pharmatutor.org/articles/buccal-drug-delivery-system
5. https://onlinelibrary.wiley.com/doi/full/10.1002/mds3.10069
6. https://link.springer.com/chapter/10.1007/978-3-031-52520-9_11