DNA Fragmentation Tests for Male Fertility Evaluation

DNA fragmentation tests are used to assess the integrity and quality of DNA in sperm samples. This test helps in evaluating male fertility potential by detecting DNA damage.

DNA fragmentation tests FAQ

Image credit: youtube.com

What is DNA fragmentation testing?

DNA fragmentation testing allows us to look at the level of damage that’s occurring to the DNA in the head of the sperm. The damage we are referring to is in relation to the strands that connect the DNA molecules together.

What is a sperm DNA fragmentation test?

Sperm DNA fragmentation is an advanced test used to determine the damage or “fragmentation” of sperm. While sperm might show good results when looking at motility and volume during a semen analysis, a DNA fragmentation test for sperm may reveal other damage which may negatively impact the sperm’s ability to fertilise an egg.

When is a DNA fragmentation test recommended?

This test is recommended for all men over the age of 45 but is also suitable for couples who have been trying to conceive for one year or are considering IVF treatment. A DNA fragmentation test is also highly recommended for patients who are experiencing recurrent spontaneous miscarriages or unexplained (idiopathic) infertility.

Is DNA fragmentation testing available on the NHS?

Currently there is no provision for DNA fragmentation testing on the NHS and it’s likely to be some time until this changes. Much as there are recommendations within the latest WHO guidance for DNA fragmentation testing it’s not being offered as standard. There is also still some controversy around the value of the test.

Is a sperm DNA fragmentation test safe?

With in-depth knowledge about your sperm health, your doctor can help you navigate the best next steps in your fertility journey. Furthermore, there are no known risks associated with a sperm DNA fragmentation test for male patients. The HFEA does provide additional information. How much does a sperm DNA fragmentation test cost?